Description
Dharmacon™ ON-TARGETplus™ 2.0 advances our Dharmacon RNAi portfolio with improved specificity and expanded transcript isoform coverage. Retaining the strengths of the legacy ON-TARGETplus modified synthetic siRNA, ON-TARGETplus 2.0 siRNAs are designed against the latest reference genome and carefully curated to ensure broad per-gene transcript isoform representation, enhancing specificity, reducing off-targets, and driving effective knockdown of transcripts—even for highly diverse genes. When combined in our SMARTpool™ siRNA format, ON-TARGETplus 2.0 enables comprehensive targeting of every gene’s unique transcript isoforms, delivering reproducible, high-confidence gene silencing for both focused experiments and large-scale screens.
